About Onsolis

If you take medicine to control constant cancer pain but experience sudden flares of breakthrough pain, Onsolis® may help.

Onsolis® is an opioid pain medicine (see next paragraph for more details). It is made with the pain medicine fentanyl (pronounced "FEN-tuh-nil"). Onsolis is a small film that is designed to stick to the inside of your cheek after you hold it in place for 5 seconds. The Onsolis film usually dissolves within 15 to 30 minutes of application.

Onsolis (fentanyl buccal soluble film) is an opioid pain medicine used only for the treatment of breakthrough pain in patients with cancer, 18 years of age or older, who are already taking another opioid for their constant cancer pain and their body is used to this medicine (opioid tolerant). Patients are opioid tolerant if they are taking at least: 60 mg oral (by mouth) morphine/day, 25 mcg transdermal (patch) fentanyl/hour, 30 mg of oral oxycodone/day, 8 mg oral hydromorphone/day, 25 mg oral oxymorphone/day, or another opioid at a dose shown to provide similar relief, for 1 week or longer.

Onsolis must not be used in patients who are not opioid tolerant because life threatening breathing problems could occur. For this reason, you should not use Onsolis if you only have pain for a short time, pain from surgery, headache, migraine, or dental pain. Onsolis should not be used in the emergency room.

Only patients with cancer who can tolerate opioid pain medicines should use Onsolis. Only health care providers with experience in treating cancer pain with these medicines should prescribe Onsolis.

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